ethyl 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetate - Names and Identifiers
ethyl 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetate - Introduction
ethyl 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetate, the chemical formula is C10H9BrF2O3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Molecular weight: 295.08g/mol
-Melting point: No data
-Boiling point: 284-286 ° C
-Density: 1.692g/cm³
Use:
ethyl 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetate is an organic compound commonly used as an intermediate and reagent in organic synthesis reactions. It can be used in pharmaceutical research, pesticide synthesis and other organic synthesis fields.
Method:
In General, ethyl 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetate can be synthesized by the following steps:
1. 4-bromo-3-methoxyphenol reacts with acetonitrile to generate the corresponding phenolic Ester compound.
2. The compound obtained in the previous step is reacted with ethyl difluoroacetate under alkaline conditions to generate the final product.
Safety Information:
-The compound is stable at room temperature, but must be stored in a cool and dry place.
-Wear appropriate personal protective equipment, such as lab gloves and safety glasses, when handling the compound.
-Avoid contact with skin, eyes and mucous membranes. For accidental contact, rinse with plenty of water and seek medical help.
-When using this compound, strictly follow the chemical safety procedures and use it in a well-ventilated laboratory.
Last Update：2024-04-09 15:18:04